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Di seguito vengono riportati gli Abstract degli articoli pubblicati sulle riviste di settore dai soci del gruppo GSC


Accertamenti chimico-tossicologici e articoli 186 e 187 codice della strada

Mattia Sicilia, Oscar Ghizzoni

Abstract

 

CONTEXT:

 

Gli accertamenti etilomentrici eseguiti su strada dalle Forze dell'Ordine spesso non tengono conto delle limitazioni degli strumenti di misura utilizzati. Analogamente, spesso le analisi condotte in ambiente ospedaliero a seguito di sinistro stradale non tengono in considerazione le problematiche di assunzione pregressa, valutabile mediante la corretta interpretazione dei dati ottenuti mediante Test di Conferma.

 

Editor:          Giuffrè Editore

 

 


Isobornyl acrylate: an impurity in alkyl glucosides

Foti C1, Romita P, Rigano L, Zimerson E, Sicilia M, Ballini A, Ghizzoni O, Antelmi A, Angelini G, Bonamonte D, Bruze M.

Abstract

 

CONTEXT:

 

Alkyl glucosides and alkyl poly-glucosides are widely used as wetting agents, surfactants and emulsifiers in several industrial and cosmetic products. They are known as well-tolerated and are usually added to the primary surfactants in order to reduce the irritating potential of the main foaming agents.

 

OBJECTIVE:

 

Recently, some authors suggested that allergic contact dermatitis to alkyl glucosides might be more frequent than suspected. On the other hand, the chemical structures of glucosides do not show  potentially allergenic chemical groups or strongly polarized structures. The aim of our study is to investigate alkyl glucosides carrying out a detailed chemical analysis on samples of raw materials to identify potentially allergenic impurities or by-products contained in commercial samples of alkyl glucosides.

 

MATERIALS

AND METHODS:

 

                                                                                                                                                                                We chemically analyzed samples of cocoyl glucoside, decyl glucoside and lauryl glucoside by three different analytical methods, in order to identify any undesired or   polluting substances.

RESULT:



In each of the three samples, we detected the presence of isobornyl acrylate. Its approximate content in the tested samples is 500 ng/g of the product.

 

DISCUSSION:

 

Isobornyl acrylate is not used in the synthesis of alkyl glucosides, but as a plasticizer in many plastic materials. It can be easily released to materials flowing over these surfaces when they have high extraction power, as glucosides.

 

CONCLUSION:

 

Isobornyl acrylate may play a role as hidden allergen, in the form of an impurity collected during the industrial process, explaining some cases of allergic reaction to alkyl glucosides.

 

editor:                                cutaneous and ocular toxicology